Pharmaceutics / Medical Equipment

Every human follows a unique circadian rhythm that regulates key physiological processes such as sleep, metabolism, hormone secretion, immune response and drug metabolism. This biological timing varies significantly between individuals and plays a critical role in determining the effectiveness and tolerability of medical treatments, as well as overall health and wellbeing. Despite its importance, circadian biology is not routinely measured or integrated into healthcare or consumer health solutions. As a result, treatments, daily routines and health interventions are often applied at suboptimal times, leading to reduced efficacy, increased side effects and missed opportunities for prevention. Technology and Solution: An innovative company from northern Germany has developed a simple, non-invasive diagnostic that enables accurate measurement of an individual’s biological clock at the molecular level. The technology determines internal biological timing, by analysing RNA biomarkers associated with circadian gene expression and applies proprietary AI and mathematical models. These data are translated into personalised, actionable guidance, including optimal timing for sleep, nutrition, physical activity, recovery and medication intake. This allows both clinicians and individuals to align interventions with the body’s natural rhythms. The solution has been clinically validated and tested in real-world settings, including partnerships with leading academic institutions such as Charité – Universitätsmedizin Berlin, and has been deployed in a reimbursed diagnostic use case in Germany. Applications and Impact: The technology enables a wide range of applications, including precision medicine (e.g. treatment timing optimisation), pharmaceutical research (clinical trial design), and consumer health (personalised daily health guidance). By making biological timing visible and actionable, the solution supports preventive health, improves patient outcomes and enhances everyday wellbeing. Partnering Opportunities: The company is seeking partners in healthcare, pharmaceuticals, digital health, diagnostics, and consumer health industries to further develop, integrate and scale this technology across clinical and non-clinical use cases. Advantages and innovations Key advantages include: - The solution introduces a new paradigm in precision medicine and everyday health optimisation. - Improved treatment outcomes – Aligning interventions with biological timing enhances efficacy and reduces side effects. - Actionable outputs – The technology translates complex data into simple, personalised recommendations for timing of treatments, sleep, nutrition and activity. - Direct biological measurement – Unlike wearables or questionnaires, the technology measures circadian rhythms at the molecular level using RNA biomarkers. - Non-invasive and scalable (easy to use) – Saliva-based testing enables easy integration into clinical workflows and consumer health applications. - Dual-market applicability – Suitable for both medical (IVD-based) and consumer health use cases, supporting prevention and self-care. - Strong scientific foundation – Based on over a decade of peer-reviewed research in chronobiology and validated in clinical and real-world settings. Technical Specification or Expertise Sought - hospitals, healthcare providers (already reimbursed by Germany’s largest health care provider) for clinical validation and implementation - Pharmaceutical R&D and clinical trials (chronotherapy integration) - Diagnostics and laboratory infrastructure - Digital health platforms and data integration - Consumer health and wellness applications (timing-based recommendations) - Distribution and market access in Europe and internationally The goal is to integrate circadian diagnostics into existing healthcare and consumer ecosystems, enabling scalable, timing-based health solutions. Expected role of a partner: Strategic partners are sought to - integrate, - validate and - scale its circadian diagnostic technology across prevention and treatment applications. Partners are expected to collaborate in implementation, co-development, validation and market deployment of timing-based health solutions. Application Area 1: Prevention (Health & Longevity): In this area, partners will integrate the circadian diagnostic into preventive and lifestyle-focused programmes, enabling personalised, timing-based interventions. We are seeking: - Clinics and longevity centres to incorporate circadian diagnostics into preventive health programmes - Dietary supplement and consumer health product manufacturers to develop “when-to-take” guidance and optimise product effectiveness - Organisations in rehabilitation, women’s health and sports to